Background:

PRDM6 is a zinc-finger domain containing protein that belongs to a family of PRDM (PRDI-BF1 and RIZ homology domain) proteins that act as agents for chromatin remodeling. The PRDM family is often associated with gene regulation and chromatin remodeling by way of their histone methyltransferase abilities. PRDM6 can function as a transcriptional repressor through interactions with the deacetylases and methyltransferases associated with Histone H4. PRDM6 is expressed in vascular precursor cells and likely has a role in development and differentiation of vascular tissue through its ability to remodel chromatin.

Specificity:

PRDM6 polyclonal antibody detects endogenous levels of PRDM6 protein.

Alternative names:

PFM3

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human PRDM6.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 80 kDa

Applications:

WB

Usage:

WB 1:500 - 1:2000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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