Background:

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ULK4 (unc-51-like kinase 4) is a 1,275 amino acid protein that contains one protein kinase domain and one HEAT repeat and belongs to the Ser/Thr protein kinase family. Although containing what is thought to be a catalytically inactive domain, ULK4 may play a role in the ATP-dependent phosphorylation of target proteins.

Specificity:

ULK4 polyclonal antibody detects endogenous levels of ULK4 protein.

Alternative names:

Serine/threonine-protein kinase ULK4; Unc-51-like kinase 4; ULK4

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human ULK4.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 160 kDa

Applications:

WB IHC IF

Usage:

WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com