Background:

Over 100 cell surface markers have been identified through the use of monoclonal antibodies. Many of these markers have proven useful in identifying a specific subpopulation of cells within a mixed colony. Accordingly, these molecules have been assigned a “cluster of differentiation” (CD) designation. CD43 is the major O-glycosylated cell-surface associated sialoglycoprotein found on the cell membranes of leukocytes. It is a member of the surface mucin family which plays a central role in cellular adhesion tumor progression. Also called leukosialin, CD43 is best known as a marker for identifying normal and neoplastic T cells and a subset of neoplastic B cells within tissues. CD43 is thought to function as a negative regulator of cellular adhesion.

Specificity:

SPN polyclonal antibody detects endogenous levels of SPN protein.

Alternative names:

Leukosialin; Galactoglycoprotein; GALGP; Leukocyte sialoglycoprotein; Sialophorin; CD43; SPN; CD43

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human SPN.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 130 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:2000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com