Background:

IRSp53 comprises a central SH3 domain, which binds to proline-rich regions of a wide range of Actin regulators, and a conserved N-terminal IRSp53/MIM homology domain (IMD) that harbors F-Actin-bundling activity. IRSp53 inter-acts with atrophin-1, the product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene, which is associated with an autosomal dominant neurodegenerative disease. The IRSp53 protein also interacts with ENAH, BAI-1, Eps8, Shank 1, Shank 2, Shank 3, WAVE1, WAVE2, Tiam1 and Dia 1.

Specificity:

BAIAP2 polyclonal antibody detects endogenous levels of BAIAP2 protein.

Alternative names:

BAI associated protein 2; BAI-associated protein 2; BAI1 associated protein 2; BAI1-associated protein 2; BAIAP 2; Baiap2; BAIP2_HUMAN; BAP2; Brain specific angiogenesis inhibitor 1 associated protein 2; Brain-specific angiogenesis inhibitor 1-associated protein 2; Fas ligand associated factor 3; Fas ligand-associated factor 3; FLAF3; Insulin receptor substrate p53; Insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa; IRS 58; IRS-58; IRSP53; IRSp53/58; Protein BAP2;

Species reactivity:

Human,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human BAIAP2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 61-65 kDa

Applications:

WB IHC IF

Usage:

WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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