Background:

This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants.

Specificity:

PELP1 polyclonal antibody detects endogenous levels of PELP1 protein.

Alternative names:

glutamic acid- and leucine-rich protein 1; HMX3; MNAR; Modulator of non-genomic activity of estrogen receptor; modulator of nongenomic activity of estrogen receptor; P160; PELP1; PELP1 proline glutamic acid leucine rich protein 1; PELP1 proline- glutamic acid- leucine-rich protein 1; PELP1_HUMAN; proline and glutamic acid rich nuclear protein; Proline-; proline-, glutamic acid- and leucine-rich protein 1; Transcription factor HMX3;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human PELP1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~160 kDa

Applications:

WB,IHC,IF

Usage:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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