Background:

The F-Actin family of capping proteins includes CapZ-α1, CapZ-α2, CapZ-α3 and CapZ-β3, all of which function in a calcium-dependent manner and bind to the fast growing barbed end of Actin filaments, thereby blocking protein exchange at these ends. The F-Actin capping protein complex is a heterodimer consisting of α and β subunits that caps the barbed ends of Actin filaments and nucleates the polymerization of Actin monomers, yet does not sever Actin filaments.

Specificity:

CAPZA2 polyclonal antibody detects endogenous levels of CAPZA2 protein.

Alternative names:

CAPPA2; Capping protein (actin filament) muscle Z line; alpha 2; CapZ alpha 2; CapZ alpha-2; CAPZ; CAPZA2; CAZA2; F actin capping protein subunit alpha 2; F-actin-capping protein subunit alpha-2;

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human CAPZA2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 38 kDa

Applications:

WB,IHC

Usage:

WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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