Background:

RMB25 (RNA binding motif protein 25), also known as S164, RNPC7, RED120 or fSAP94, is a 784 amino acid protein that contains one PWI domain and one RRM (RNA recognition motif) domain. Localized to the cytoplasm, as well as to nuclear speckles, RBM25 functions as a splicing factor that is thought to stabilize the pre-mRNA-U1 snRNP complex and may couple splicing with mRNA 3'-end formation. The gene encoding RBM25 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD).

Specificity:

RBM25 polyclonal antibody detects endogenous levels of RBM25 protein.

Alternative names:

fSAP94;NET52;RED120;RNPC7;S164;Snu71

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human RBM25

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 120 kDa

Applications:

WB,IF

Usage:

WB 1:500 - 1:2000 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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