Background:

Prostate epithelium-specific Ets transcription factor (PDEF), also designated prostate Ets or SAM pointed domain containing Ets transcription factor, is a 335 amino acid nuclear protein. PDEF belongs to the Ets family of proteins. This protein, which localizes to prostate epithelial cells, functions as an Ets transcription factor. It upregulates the activity of the p62 promotor but this activity can be downregulated by PSI. It is also involved in the activation of prostate-specific antigen (PSA) by acting as an androgen-independent transactivator.

Specificity:

SPDEF polyclonal antibody detects endogenous levels of SPDEF protein.

Alternative names:

SAM pointed domain-containing Ets transcription factor; Prostate epithelium-specific Ets transcription factor; Prostate-specific Ets; Prostate-derived Ets factor; SPDEF; PDEF; PSE

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human SPDEF.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 50 kDa

Applications:

WB IHC IF

Usage:

WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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Email: info@sobekbio.com

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