Background:

The Lipase family belongs to one of the most robust genetic superfamilies found in living organisms that includes esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Balancing the composition and the transport of lipoproteins in human plasma is essential for normal body function and is mediated in part by Hepatic Lipase, also known as HL or LIPC. Rare deficiencies in Hepatic Lipase have been identified in humans which lead to pathologic levels of circulating lipoprotein particles; this condition is associated with coronary artery disease (CAD).

Specificity:

LIPC polyclonal antibody detects endogenous levels of LIPC protein.

Alternative names:

Hepatic triacylglycerol lipase; Short name=HL; Hepatic lipase; Lipase member C; LIPC; HTGL

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human LIPC.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

Refer to figures

Applications:

WB IF

Usage:

WB: 1:500~1:2000 IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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