Background:

The tumor protein D52 (TPD52) family consists of three members, TPD52, TPD52L1 (D53) and TPD52L2 (D54). These small coiled-coil motif bearing proteins interact in hetero- and homomeric fashion. The TPD52 gene maps to chromosome 8q21.13 and due to amplification, shows frequent overexpression in prostate and breast carcinomas. TPD52 binds to annexin VI in a Ca2+-dependent manner, suggesting that these molecules may act in concert to regulate secretory processes in plasma cells.

Specificity:

TPD52 polyclonal antibody detects endogenous levels of TPD52 protein.

Alternative names:

D52; N8L; PC-1; PrLZ; hD52;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human TPD52

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 26 kDa

Applications:

WB IHC

Usage:

WB 1:1000 - 1:2000 IHC 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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