Background:

RGS13 (regulator of G protein signaling 13) localizes in membrane and nuclear fractions, and is expressed predominantly in tonsil, thymus, lymph node, lung and spleen tissues. Within the lymphoid compartment, highest levels of RGS13 have been found in resting CD19-positive (B cells). Unlike most RGS proteins, RGS13 has no recognizable domain other than the RGS box, but because of its pre-valence in the immune system and lung and its ability to inhibit Gaq, Gai and cAMP generation, the function of RGS13 might be to modulate specific G protein-dependent signal transduction pathways in these regions.

Specificity:

RGS13 polyclonal antibody detects endogenous levels of RGS13 protein.

Alternative names:

Regulator of G-protein signaling 13

Species reactivity:

Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human RGS13.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 30 kDa

Applications:

WB,IHC

Usage:

WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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