Background:

Nur77 (also designated NGFI-B), Nurr1 (Nur-related factor 1) and NOR-1 (neuron-derived orphan receptor-1) constitute the NGFI-B subfamily within the nuclear receptor superfamily.The human NOR-1 gene maps to chromosome 9q and encodes a protein which is expressed in heart, skeletal muscle, thymus and spleen as well as in brain, where it is developmentally regulated. Therefore, NOR-1 may be involved in regulating neural differentiation. The NOR-1 gene also undergoes chromosomal translocation with the EWS gene to produce a protein thought to affect pre-mRNA splicing.

Specificity:

NOR-1 (Y419) polyclonal antibody detects endogenous levels of NOR-1 protein.

Alternative names:

Nuclear receptor subfamily 4 group A member 3; Mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; Nuclear hormone receptor NOR-1; NR4A3; CHN; CSMF; MINOR; NOR1; TEC

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 389-435 of Human NOR-1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 68 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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