Background:

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase to endosomes from the Golgi and back again. Cargo selection protein TIP47, also designated placental protein 17, is required for the transport from endosomes to the trans-Golgi network and interacts with the cytoplasmic domains of both cation-dependent and cation-independent MPRs. Another member of the peripilin family, Adipophilin (ADRP), is a protein associated with the globule surface membrane material of milk lipid globules. The phos-phoprotein Perilipin (Peri) is located on the surface of intracellular lipid droplets within adipocytes where it protects lipid storage droplets by coating them in adipocytes until they are digested by lipase. As a critical regulator of lipolysis, elevated Perilipin levels have been linked to obesity.

Specificity:

ADFP polyclonal antibody detects endogenous levels of ADFP protein.

Alternative names:

Perilipin-2; Adipophilin; Adipose differentiation-related protein; ADRP; PLIN2; ADFP

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human ADFP.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 48 kDa

Applications:

WB,IHC,IF

Usage:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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