Background:

May be involved in the transcriptional activation of MDM2 and EP300 genes. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 1 KRAB domain. Contains 1 SCAN box domain. Contains 7 C2H2-type zinc fingers. tissue specificity:Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.

Specificity:

ZKSCAN4 polyclonal antibody detects endogenous levels of ZKSCAN4 protein.

Alternative names:

Zinc finger protein with KRAB and SCAN domains 4;P373c6.1; Zinc finger protein 307; Zinc finger protein 427; ZKSCAN4; ZNF307; ZNF427

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Immunogen:

Synthetic peptide, corresponding to Human ZKSCAN4.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 65 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:1000 IHC:1:50~1:100

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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