Background:

Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) or solute carrier 30 (SLC30) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT proteins also belong to the cation diffusion facilitator (CDF) transporter family of metal ion transporters. ZnT-9, also known as HUEL (human embryonic lung protein), GAC63 (GRIP1-associated coactivator 1) or SLC30 member 9, displays ubiquitous expression in fetal and adult tissues as well as cancer cell lines. ZnT-9 localizes to the cytoplasm and is translocated to the nucleus during S phase. ZnT-9 has the lowest homology with the other zinc transporters and may function as a DNA-binding protein.

Specificity:

ZNT9 polyclonal antibody detects endogenous levels of ZNT9 protein.

Alternative names:

Zinc transporter 9; ZnT-9; Human embryonic lung protein; HuEL; Solute carrier family 30 member 9; SLC30A9; C4orf1; HUEL

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to Human ZNT9.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 55 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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