Background:

ADPGK (ADP-dependent glucokinase), also known as ADP-GK or RbBP-35, is a member of the ADP-dependent glucokinase family of proteins that are involved in both carbohydrate degradation and glycolysis. Expressed in a wide variety of tissues including lymphatic, endocrine, muscular and epithelial, ADPGK functions to catalyze the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate. Although GDP and CDP can replace ADP as a phosphate donor, the enzymatic efficiency of ADPGK is decreased when anything other than ADP is used. ADPGK contains one ADPK (ADPdependent kinase) domain and is able to bind one magnesium ion as a cofactor. Five isoforms of ADPGK exist due to alternative splicing events.

Specificity:

ADPGK polyclonal antibody detects endogenous levels of ADPGK protein.

Alternative names:

ADP-dependent glucokinase; ADP-GK; ADPGK; RbBP-35; ADPGK

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Immunogen:

Synthetic peptide, corresponding to Human ADPGK.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 45-55kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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