Background:

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,

Specificity:

PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein.

Alternative names:

TAOK1; KIAA1361; MAP3K16; MARKK; Serine/threonine-protein kinase TAO1; Kinase from chicken homolog B; hKFC-B; MARK Kinase; MARKK; Prostate-derived sterile 20-like kinase 2; PSK-2; PSK2; Prostate-derived STE20-like kinase 2; Thousand and one

Species reactivity:

Human

Host:

Rabbit

Ig type:

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Immunogen:

The antiserum was produced against synthesized peptide derived from human TAOK1. AA range:431-480

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Molecular weight:

~ 120 kDa

Applications:

WB,IHC-p,IF(paraffin section),ELISA

Usage:

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For

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