Background:

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

Specificity:

phospho-RACGAP1 (Ser387) Polyclonal Antibody detects endogenous levels of RACGAP1 alpha protein only when phosphorylated at Ser387.

Alternative names:

RACGAP1 (phospho S387); p-RACGAP1(S387); p-RACGAP1(Ser387); GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.

Species reactivity:

Human,Mouse,Rat,Dog,Cow,

Host:

Rabbit

Ig type:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Immunogen:

KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387:RI(p-S)GC

Purification & Purity:

affinity purified by Protein A

Molecular weight:

71kDa

Applications:

WB,

Usage:

WB=1:500-2000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com