Background:

PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG.

Specificity:

RHBDD3 Polyclonal Antibody detects endogenous levels of RHBDD3 protein.

Alternative names:

C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3.

Species reactivity:

Human,Mouse,Rat,

Host:

Rabbit

Ig type:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Immunogen:

KLH conjugated synthetic peptide derived from human RHBDD3:151-250/386

Purification & Purity:

affinity purified by Protein A

Molecular weight:

51 kD

Applications:

WB,

Usage:

WB=1:500-2000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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