Background:

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family

Specificity:

HSD17B6 Polyclonal Antibody detects endogenous levels of HSD17B6 protein.

Alternative names:

17-beta-HSD 6; 17-beta-HSD6; 17-beta-hydroxysteroid dehydrogenase type 6; 3 hydroxysteroid epimerase; 3(alpha >beta) hydroxysteroid epimerase; 3(alpha >beta) hydroxysteroid epimerasel; 3-alpha->beta-HSE; 3-alpha->beta-hydroxysteroid epimerase; H17B6_HUMAN; HSD17B6; HSE; Hydroxysteroid (17 beta) dehydrogenase 6; Hydroxysteroid (17 beta) dehydrogenase 6 homolog (mouse); Hydroxysteroid 17 beta dehydrogenase 6; NAD+ dependent 3 alpha hydroxysteroid dehydrogenase 3 hydroxysteroid epimerase; NAD+ dependent 3 alpha hydroxysteroid dehydrogenase; Oxidative 3 alpha hydroxysteroid dehydrogenase; Oxidative 3-alpha hydroxysteroid dehydrogenase; Oxidoreductase; Retinol dehydrogenase; RODH; SDR9C6;Short chain dehydrogenase/reductase family 9C, member 6.

Species reactivity:

Human,Mouse,Rat,Pig,Horse,

Host:

Rabbit

Ig type:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Immunogen:

KLH conjugated synthetic peptide derived from human HSD17B6:61-160/317

Purification & Purity:

affinity purified by Protein A

Molecular weight:

33kDa

Applications:

FCM,

Usage:

Flow-Cyt=1ug/Test

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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