Background:

This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.

Specificity:

phospho-HMGCR (Ser872) Polyclonal Antibody detects endogenous levels of HMGCR protein only when phosphorylated at Y872.

Alternative names:

phospho-HMGCR (S872); HMGCR (phospho-Ser872); HMGCR (phospho S872); 3 hydroxy 3 methylglutaryl CoA reductase; 3 hydroxy 3 methylglutaryl Coenzyme A reductase; 3 hydroxymethylglutaryl CoA reductase; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); 3-hydroxy-3-methylglutaryl-coenzyme A reductase; 3H3M; HMDH_HUMAN; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; Hydroxymethylglutaryl CoA reductase; LDLCQ3; MGC103269; Red.

Species reactivity:

Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,

Host:

Rabbit

Ig type:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Immunogen:

KLH conjugated Synthesised phosphopeptide derived from human HMGCR around the phosphorylation site of Ser872:NR(p-S)KI

Purification & Purity:

affinity purified by Protein A

Molecular weight:

~97 kDa

Applications:

FCM,

Usage:

Flow-Cyt=1ug/Test

Storage:

Store at 4°C short term. Aliquot and store at -55°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com