Background:

This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]

Specificity:

ALOX12 Polyclonal Antibody detects endogenous levels of ALOX12 protein.

Alternative names:

12 Lox; 12(S) lipoxygenase; 12S LOX; Alox 12; Alox12L; Alox15; Arachidonate 12 lipoxygenase 12S type; Arachidonate 12 lipoxygenase; Arachidonate 12 lipoxygenase leukocyte type; Arachidonate 12 lipoxygenase, 12S type; Arachidonate 12 lipoxygenase, leukocyte type; EC1.13.11.31; LOG 12; LOG12; Platelet type 12 lipoxygenase; Platelet type lipoxygenase 12; P-12-LOX; LOX12_HUMAN; 12 Lipoxygenase.

Species reactivity:

Human,Mouse,Rat,Cow,

Host:

Rabbit

Ig type:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Immunogen:

KLH conjugated synthetic peptide derived from human 12 Lipoxygenase:101-200/663

Purification & Purity:

affinity purified by Protein A

Molecular weight:

~76 kDa

Applications:

WB,

Usage:

WB=1:500-2000

Storage:

Store at 4°C short term. Aliquot and store at -46°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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