Background:

This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]

Specificity:

phospho-NeuroD1 (Ser274)Polyclonal Antibody detects endogenous levels of NeuroD1 protein only when phosphorylated at Y274.

Alternative names:

NeuroD1 (phospho S274); p-NeuroD1 (phospho S274); atonal; basic helix loop helix transcription factor; BETA 2; Beta cell E box transactivator 2; BETA2; BHF 1; BHF1; bHLHa3; class A basic helix loop helix protein 3; Class A basic helix-loop-helix protein 3; MODY 6; MODY6; NDF1_HUMAN; NEUROD; NeuroD1; Neurogenic differentiation 1; Neurogenic differentiation factor 1; neurogenic helix loop helix protein NEUROD; NIDDM

Species reactivity:

Human,Mouse,Rat,Pig,Cow,Sheep,

Host:

Rabbit

Ig type:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Immunogen:

KLH conjugated Synthesised acetylpeptide derived from human NeuroD1 around the acetylation site of Ser274:PL(p-S)PP

Purification & Purity:

affinity purified by Protein A

Molecular weight:

~40 kDa

Applications:

IHC-P,

Usage:

IHC-P=1:100-500

Storage:

Store at 4°C short term. Aliquot and store at -6°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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