Background:

Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.

Specificity:

LCLAT1 Polyclonal Antibody detects endogenous levels of LCLAT1 protein.

Alternative names:

1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; Acyl-CoA:lysocardiolipin acyltransferase 1; AGPAT8; ALCAT1; HSRG1849; lclat1; LCLT1_HUMAN; LYCAT; Lysocardiolipin acyltransferase 1; UNQ1849; UNQ1849/PRO3579

Species reactivity:

Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,

Host:

Rabbit

Ig type:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Immunogen:

KLH conjugated synthetic peptide derived from human LCLAT1:261-360/414

Purification & Purity:

affinity purified by Protein A

Molecular weight:

~49 kDa

Applications:

WB,

Usage:

WB=1:500-2000

Storage:

Store at 4°C short term. Aliquot and store at -19°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com