Background:

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. Can also hydrolyze CTP and the modified nucleotides pseudo-UTP, 5-methyl-UTP (m5UTP) and 5-methyl-CTP (m5CTP). Has weak activity with dCTP, 8-oxo-GTP and N4-methyl-dCTP.May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.In addition, the presence of the putative catalytic domain of S-adenosyl-L-methionine binding in the C-terminal region argues for a methyltransferase activity (Probable).

Specificity:

Recognizes endogenous levels of ASMTL protein.

Alternative names:

N-acetylserotonin O-methyltransferase-like protein; ASMTL

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Immunogen:

Recombinant full length protein of human ASMTL

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 75 kDa

Applications:

WB, IHC

Usage:

WB (1/500 - 1/2000), IHC (1/50 - 1/200)

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com