Background:

Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

Specificity:

Recognizes mouse CD152

Alternative names:

CD152; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152

Species reactivity:

Mouse

Host:

Syrian Hamster

Ig type:

Syrian Hamster IgG. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Immunogen:

Mouse CTLA-4-mouse IgG2a fusion protein

Purification & Purity:

The monoclonal antibody was affinity-purified from Syrian Hamster antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 25 kDa

Applications:

IF, FC

Usage:

IF (1/50 - 1/200)

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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