Histone H2A (AcK118) polyclonal antibody BS67181
Specifications
| 50ul/100ul |
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Specificity:
Recognizes endogenous levels of Histone H2A with an acetylation site at K118 protein.
Alternative names:
HIST1H2AG; H2AFP; HIST1H2AI; H2AFC; HIST1H2AK; H2AFD; HIST1H2AL; H2AFI; HIST1H2AM; H2AFN; Histone H2A type 1; H2A.1; Histone H2A/p; H2AFX; H2AX; Histone H2A.x; H2a/x
Species reactivity:
Human,Rat,Mouse
Host:
Rabbit
Ig type:
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen:
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Histone H2A with an acetylation site at K118. The exact sequence is proprietary.
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 142% (by SDS-PAGE).
Molecular weight:
~ 15 kDa
Applications:
WB
Usage:
WB (1/500 - 1/1000)
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
