Background:

HSPA2 (heat shock 70kDa protein 2), also known as HSP70-2 or HSP70-3, is a 639 amino acid member of the heat shock 70 (HSP 70) family of proteins and is widely expressed with highest levels detected in testis and skeletal muscle. Like other members of the HSP 70 family, HSPA2 cooperates with chaperone proteins to both prevent protein aggregation and mediate the folding of newly expressed polypeptides in the cytosol. Through its ability to chaperone and regulate protein folding, HSPA2 is thought to be crucial for proper sperm maturation and function. Overexpression of HSPA2 is associated with breast cancer, suggesting a possible role for HSPA2 in tumor formation

Specificity:

HSPA2 polyclonal antibody detects endogenous levels of HSPA2 protein.

Alternative names:

HSP70-2; HSP70-3;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human HSPA2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 70 kDa

Applications:

WB,IF

Usage:

WB 1:500 - 1:2000 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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