Background:

Human TRP1 protein is a 793 amino acid cation channel that is expressed in fetal and adult brain and in adult heart, testis and ovary, where it may influence store-operated Ca2+ entry as a component of capacitative calcium entry (CCE) complexes. The brain-specific subunit TRP5 forms a nonselective cation channel with TRP1 in the hippocampus that is activated by Gq-coupled receptors, but not by depletion of intracellular Ca2+ stores. The gene encoding human TRP5 maps to chromosome Xp23, which also contains loci for nonsyndromic mental retardation and X-linked disorders.

Specificity:

TRPC5 polyclonal antibody detects endogenous levels of TRPC5 protein.

Alternative names:

Short transient receptor potential channel 5; TrpC5; Transient receptor protein 5; TRP-5; hTRP-5; hTRP5; TRPC5; TRP5

Species reactivity:

Human,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human TRPC5.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 111 kDa

Applications:

WB IHC

Usage:

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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