Background:

RBM22, also designated Zinc finger CCCH domain-containing protein 16, is a highly conserved RNA binding protein that is predominantly expressed in spleen and is localized to the nucleus. With a RRM (RNA recognition motif domain) and a C3H1-type zinc finger, RBM22 is primarily involved in pre-mRNA splicing. In the presence of RBM22, cytosolic ALG-2 (Apoptosis Linked Gene 2) translocates to the nucleus, suggesting a functional interaction between the two proteins. Homologs of RBM22 are essential proteins in the regulation of alternative splicing in the cell cycle, zebrafish development and Drosophilia heart development.

Specificity:

RBM22 polyclonal antibody detects endogenous levels of RBM22 protein.

Alternative names:

Pre-mRNA-splicing factor RBM22; RNA-binding motif protein 22; Zinc finger CCCH domain-containing protein 16; RBM22; ZC3H16

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human RBM22.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 47 kDa

Applications:

WB

Usage:

WB 1:500 - 1:2000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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