Background:

GABARAPL2 (γ-aminobutyric acid receptor-associated protein-like 2), also known as ATG8, GEF2 (ganglioside expression factor 2), ATG8C or GATE16 (golgi-associated ATPase enhancer of 16 kDa), is a 117 amino acid protein belonging to the MAP1 LC3 family. Localized to Golgi apparatus, GABARAPL2 is ubiquitously expressed. Very high levels of GABARAPL2 are found in brain, heart, prostate, ovary, spleen and skeletal muscle. GABARAPL2 is subject to post-translational modifications, including phosphorylation, which is thought to occur in response to DNA damage by ATM or ATR. GABARAPL2 is involved in intra-Golgi traffic and modulates intra-Golgi transport through coupling between NSF and SNAREs activation. GABARAPL2 interacts with GABAA Rγ2, NSF, GS28, β Tubulin and ULK1.

Specificity:

GABARAPL2 polyclonal antibody detects endogenous levels of GABARAPL2 protein.

Alternative names:

ATG8; GEF2; ATG8C; GEF-2; GATE16; GATE-16;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human GABARAPL2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 14 kDa

Applications:

WB IHC IF

Usage:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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