Background:

Small synthetic molecules called growth-hormone secretagogues (GHSs) act through GSH-R to stimulate the release of GH from the pituitary. Ghrelin is an endogenous levels of ligand for the growth hormone secretagogue receptor (GHS-R). Ghrelin and GHRH are involved in the regulation of GH release from the pituitary. GHRH exerts its action through high-affinity GHRH receptors (GHRH-R) present in the anterior pituitary. The acylated peptide of ghrelin specifically releases GH both in vivo and in vitro and is found in stomach tissue. GH plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. The gene encoding ghrelin maps to human chromosome 3p26-p25.

Specificity:

Ghrelin polyclonal antibody detects endogenous levels of Ghrelin protein.

Alternative names:

Appetite regulating hormone; Ghrelin 27; Ghrelin 28; Ghrelin; Ghrelin/obestatin prepropeptide; ghrl; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; Growth hormone-releasing peptide; M46 protein; Motilin related peptide; Motilin-related peptide; MTLRP; Obestatin; Protein M46;

Species reactivity:

Human,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human Ghrelin.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 13 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:2000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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