Background:

Dynactin, a multisubunit complex, is a cytoplasmic dynein-interacting protein that functions as the ‘receptor’ for the dynein microtubule motor. Dynactin-dynein binding may be required for most, if not all, cytoplasmic dynein driven activities and is thought to contribute to dynein’s functional diversity. Dynactin, enriched in neurons, also binds to microtubules and has been shown to function in diverse processes, including organelle transport, formation of the mitotic spindle and cytokinesis. Dynactin subunits include p22, p50, p62, p150, (also designated Glued), and Arp1.

Specificity:

DCTN1 polyclonal antibody detects endogenous levels of DCTN1 protein.

Alternative names:

150 a dynein associated polypeptide; 150 a dynein-associated polypeptide; DAP 150; DAP-150; DAP150; DCTN 1; DCTN1; DCTN1; DP 150; DP-150; DP150; Dynactin 1 (p150 Glued (Drosophila) homolog); dynactin 1 (p150 glued homolog Drosophila); Dynactin 1; Dynactin subunit 1; Dynactin1; HMN7B; p135; p150 Glued (Drosophila) homolog; p150 glued; p150 glued homolog; p150(GLUED) DROSOPHILA HOMOLOG OF; p150-glued; p150glued;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human DCTN1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 150 kDa

Applications:

WB,IF

Usage:

WB 1:500 - 1:2000 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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