Background:

Iba1, also designated AIF-1 for allograft inflammatory factor-1, is a cytoplasmic, cytokine-induced, calcium-binding protein first discovered in rat cardiac allografts with chronic rejection. Iba1 is expressed in various human immune-related tissues and may play a role in macrophage activation and function. It is a marker of human microglia and is expressed by macrophages in injured skeletal muscle. Iba1 regulates reduced proliferation and differentiation of satellite cells.

Specificity:

AIF1 polyclonal antibody detects endogenous levels of AIF1 protein.

Alternative names:

Allograft inflammatory factor 1; AIF-1; Ionized calcium-binding adapter molecule 1; Protein G1; AIF1; G1; IBA1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human AIF1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 17 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:2000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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