Bioworld Technology

Bioworld Technology is manufacturer of over 15,000 highly purified Monoclonal and Polyclonal Antibodies, Peptides, Proteins, and other related Research Products. Their products are used in all biological fields. An important focus in research taking place today is in work investigating Signal transduction pathways, Cardiac markers, Neuroscience as well as Stem cell research. Bioworld Technology is committed to providing customers with innovative research tools and to helping scientists determine the mechanisms of cell function and disease.
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TUBB2A (Acetyl-K379) polyclonal antibody BS64103

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Specifications

size	50ul/100ul

Background:

Tubulin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubulin. a and b tubulins form heterodimers which multimerize to form a microtubule filament. Multiple b Tubulin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. g Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both d Tubulin and e Tubulin are associated with the centrosome. d Tubulin is a homolog of the Chlamydomonas d Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. e Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.

Specificity:

TUBB2A (Acetyl-K379) polyclonal antibody detects endogenous levels of TUBB2A protein only when acetylated at Lys379. This antibody also recognizes TUBB2B/3/4A/4B/6 protein when acetylated at the corresponding residues.

Alternative names:

Tubulin beta-2A chain; Tubulin beta class IIa; TUBB2A; Tubulin beta-2B chain; TUBB2B; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III; TUBB3; Tubulin beta-4B chain; Tubulin beta-2 chain; Tubulin beta-2C chain; TUBB4B; Tubulin beta chain; Tubulin beta-5 chain; TUBB; Tubulin beta-6 chain; Tubulin beta class V; TUBB6

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic Acetylated peptide derived from human TUBB2A around the Acetylation site of K379.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 49 kDa

Applications:

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com