Background:

RRP7A (ribosomal RNA processing 7 homolog A), also known as CGI-96 or gastric cancer antigen Zg14, is a 280 amino acid protein that contains one RRM domain. RRP7A is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.

Specificity:

RRP7A/RRP7B polyclonal antibody detects endogenous levels of RRP7A/RRP7B protein.

Alternative names:

Ribosomal RNA-processing protein 7 homolog A; Gastric cancer antigen Zg14; RRP7A; CGI-96; Putative ribosomal RNA-processing protein 7 homolog B; Putative gastric cancer antigen Zg14-like protein; RRP7BP; RRP7B

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 230-280 of Human RRP7A.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 32 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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