Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF498 (zinc finger protein 498), also known as Zinc finger and SCAN domain-containing protein 25 (ZSCAN25), is a 544 amino acid protein. Localized to the nucleus, ZNF498 contains seven C2H2-type zinc fingers and one SCAN box domain. Due to the presence of these domains, ZNF498 is believed to be involved in transcriptional regulation. ZNF498 exists as 4 isoforms produced by alternative splicing.

Specificity:

ZNF498 polyclonal antibody detects endogenous levels of ZNF498 protein.

Alternative names:

Zinc finger and SCAN domain-containing protein 25; Zinc finger protein 498

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 115-159 of Human ZNF498.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 106% (by SDS-PAGE).

Molecular weight:

~ 61 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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