Background:

Apolipoproteins are a family of fatty-acid binding proteins that transport fat through the bloodstream in the form of lipoproteins. ApoO functions to promote the transport of cholesterol from macrophage cells and may be involved in regulatory mechanisms that protect lipid accumulation within the heart. ApoO is present in high density lipoproteins (HDLs) and low density lipoproteins (LDLs), and is secreted by an MTP (microsomal triglyceride transfer protein)-dependent mechanism. ApoOL (apolipoprotein O-like), also known as FAM121A, is a 268 amino acid secreted protein belonging to the apolipoprotein O family and may be involved in cholesterol transport. ApoOL is encoded by a gene located on human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

Specificity:

APOOL polyclonal antibody detects endogenous levels of APOOL protein.

Alternative names:

MICOS complex subunit MIC27; Apolipoprotein O-like; Protein FAM121A

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 224-268 of Human APOOL

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Molecular weight:

~ 34 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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