Background:

Olfactory receptors are G protein-coupled receptor proteins that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction cascade that leads to the production of cAMP via an olfactory-enriched adenylate cyclase. This event ultimately leads to transmission of action potentials to the brain and the subsequent perception of smell. OR4B1 (Olfactory receptor 4B1), also known as Olfactory receptor OR11-106, is a 309 amino acid multi-pass membrane protein that functions as an odorant receptor, effectively binding odor molecules and initiating the propagation of signals to the primary olfactory cortex.

Specificity:

OR4B1 polyclonal antibody detects endogenous levels of OR4B1 protein.

Alternative names:

Olfactory receptor 4B1; OST208; Olfactory receptor OR11-106; OR4B1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 264-309 of Human OR4B1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 34 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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