Background:

CTXL, a cortical thymocyte marker, is a member of the immunoglobulin (Ig) superfamily and has features of both antigen specific receptors and adhesion molecules. This single pass, type I protein contains a signal peptide, an extracellular V type Ig like domain followed by a C2 type Ig like domain and a cytoplasmic tail. Expression levels of CTXL are high in the stomach, colon, prostate, trachea, and thyroid gland, with lower levels observed in bladder and lung tissues. CTXL is not expressed in the thymus. CTXL is developmentally regulated and may be involved in thymocyte selection. It localizes to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion and transmigration of leukocytes.

Specificity:

VSIG2 polyclonal antibody detects endogenous levels of VSIG2 protein.

Alternative names:

V-set and immunoglobulin domain-containing protein 2; Cortical thymocyte-like protein; CT-like protein; VSIG2; CTH; CTXL; UNQ2770/PRO7154

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 233-278 of Human VSIG2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 34 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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