Background:

TRAPPC5 (trafficking protein particle complex 5), also known as TRS31, is a 181 amino acid protein belonging to the TRAPP (transport protein particle) small subunits family and the BET3 subfamily. Encoded by a gene that maps to human chromosome 19p13.2, TRAPPC5 is part of the multisubunit TRAPP tethering complex,which acts as a GTP exchange factor. Evolutionarily conserved, TRAPPC5 plays a role in protein binding,vesicle-mediated transport and nucleotide exchange stimulation. TRAPPC5 also performs guanine nucleotide exchanger factor (GEF) functions both in vitro and in vivo.Localizing to the Golgi apparatus, TRAPPC5 is essential for endoplasmic reticulum(ER)-to-Golgi and intra-Golgi vesicle trafficking in yeast, aswell as additional transport events in mammals,such as post--Golgi trafficking.

Specificity:

TRAPPC5 polyclonal antibody detects endogenous levels of TRAPPC5 protein.

Alternative names:

Trafficking protein particle complex subunit 5; TRAPPC5

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 68-113 of Human TRAPPC5.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 20 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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