Background:

PAGE-3 (prostate-associated gene 3 protein), also known as GAGED1 (putative G antigen family Dmember 1), is a 113 amino acid protein that belongsto the GAGE family. The gene that encodes PAGE-3 consists of approximately 6,432 bases andmapsto human chromosome Xp11.21. Chromosome X consists of about 153million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number ofconditionsrelated to an unusual number and combination ofsexchromosomes being inherited, including Turner’s syndrome, Klinefelter’ssyndrome and Triple X syndrome. Color blindness, hemophilia, and Duchennemuscular dystrophy arewellknown X chromosome-linked conditionswhich affectmalesmore frequently as males carry a single X chromosome.

Specificity:

PAGE3 polyclonal antibody detects endogenous levels of PAGE3 protein.

Alternative names:

P antigen family member 3; PAGE-3; G antigen family D member 1; Prostate-associated gene 3 protein; PAGE3; GAGED1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human PAGE3.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 12 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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