Background:

Heterotrimeric G proteinsfunction to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus(a photon, pheromone, odorant, hormone or neuro transmitter) while the effectors(e.g., adenylcyclase),which act to generate one ormore intracellula rmessengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits,since these proteins bind and hydrolyze GTP andmost obvously regulate the activity of the beststudied effectors. Evidence, however, has established an important regulatory role for the βγ subunits. It is becoming increasingly clear that different G protein complexes expressed in diffeent tissues carry structurally distinct members of the γ aswell astheαand β subunits and that preferential associations between members of subunit families increase G protein functional diversity.

Specificity:

GNG5 polyclonal antibody detects endogenous levels of GNG5 protein.

Alternative names:

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5; GNG5; GNGT5

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human GNG5.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 7 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com