Background:

ADAMDEC1 (ADAM-like, decysin 1), also known as decysin, is a 470 amino acid secreted protein that belongs to the disintegrin metalloproteinase family. Expressed primarily in dendritic cells (DCs) of the small intestine, spleen and lymph nodes, ADAMDEC1 can bind one zinc ion per subunit and is thought to be involved in controlling the immune response. ADAMDEC1 expression is induced in maturing DC cells in response to T-cell signals and its expression is upegulated during differentiation of primary monocytes into macrophages. ADAMDEC1 contains one peptidase M12B domain, a prematurely terminated disintegrin domain and, unlike other ADAM family members, does not have an intracellular tail or a cysteine-rich domain.

Specificity:

ADAMDEC1 polyclonal antibody detects endogenous levels of ADAMDEC1 protein.

Alternative names:

ADAM DEC1 (EC:3.4.24.-); A disintegrin and metalloproteinase domain-like protein decysin-1; ADAM-like protein decysin-1; ADAMDEC1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human ADAMDEC1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 53 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:1000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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