Background:

T lymphocyte surface antigen Ly9 (CD229), also designated lymphocyte antigen 9 or cell-surface molecule Ly9, is a cell surface glycoprotein. CDC229 is a Type I membrane protein that is crucial in adhesion reactions between T lymphocytes and accessory cells (homophilic interaction). It belongs to the CD2 subfamily of the immunoglobulin gene superfamily of proteins (along with CD2, CD48, CD58, CD84, CD244 and CD150). Receptors of this family are important in cytokine production regulation and cytotoxicity of lymphocytes and NK cells. CD229 interacts with the SAP/SH2D1A protein. CD229 is expressed on mature B cells, T cells, thymocytes and NK cells.

Specificity:

LY9 polyclonal antibody detects endogenous levels of LY9 protein.

Alternative names:

T-lymphocyte surface antigen Ly-9; Cell surface molecule Ly-9; Lymphocyte antigen 9; SLAM family member 3; SLAMF3; Signaling lymphocytic activation molecule 3; CD229; LY9

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human LY9.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 57,72 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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