Background:

HSPBAP1 (HSPB (heat shock 27kDa) associated protein 1), also known as PASS1 (protein associated with small stress protein 1), is a 488 amino acid cytoplasmic protein that contains one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog, PASS1. Widely expressed with highest expression in ovary, thymus and pancreas, HSPBAP1 is thought to play a role in mediating cellular stress responses within the cell. Due to the presence of a JMJC domain, HSPBAP1 may be involved in chromatin remodeling events. Defects or translocations in the gene encoding HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), suggesting a possible role for HSPBAP1 in carcinogenesis. Three isoforms of HSPBAP1 exist due to alternative splicing events.

Specificity:

HSPBAP1 polyclonal antibody detects endogenous levels of HSPBAP1 protein.

Alternative names:

HSPB1-associated protein 1; 27 kDa heat shock protein-associated protein 1; Protein associated with small stress protein 1; HSPBAP1; PASS1

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human HSPBAP1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 32 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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