Background:

HEATR1 (HEAT repeat containing 1), also known as BAP28, is a 2,144 amino acid nuclear protein involved in nucleolar processing of pre-18S ribosomal RNA. HEATR1 is a member of the HEATR1/UTP10 family and contains one HEAT repeat. The gene encoding HEATR1 is located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Specificity:

HEATR1 polyclonal antibody detects endogenous levels of HEATR1 protein.

Alternative names:

HEAT repeat-containing protein 1; Protein BAP28; N-terminally processed; HEATR1; BAP28

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human HEATR1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 242 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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