Background:

Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner.Activated by guanine nucleotide-exchange factors (GEF) EPAC and EPAC2 in a cAMP-dependent manner, and GFR.

Specificity:

RAP1A polyclonal antibody detects endogenous levels of RAP1A protein.

Alternative names:

C21KG; G 22K; G-22K; GTP binding protein smg p21A; GTP-binding protein smg p21A; KREV 1; KREV1; RAP 1A; RAP1; RAP1A; RAP1A member of RAS oncogene family; RAP1A; Ras related protein Krev 1; Ras related protein Rap 1A; RAS related protein RAP1A; Ras-related protein Krev-1; Ras-related protein Rap-1A; SMGP21;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human RAP1A.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 21 kDa

Applications:

WB,IHC,IF

Usage:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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Email: info@sobekbio.com

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