Bioworld Technology

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B4GALT6 polyclonal antibody BS60629

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Specifications

size	50ul/100ul

Background:

β-1,4-galactosyltransferases (β-1,4-Gal-T) are type II membrane-bound glycoproteins that are substrate-specific and function to transfer galactose in a β-1,4 linkage to an acceptor sugar. There are seven members of the β-1,4-Gal-T family, all of which are directed to the Golgi apparatus through a hydrophobic sequence at the N-terminus. β-1,4-Gal-T6, also known as B4GALT6, is a 382 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and belongs to the β-1,4-galactosyltransferase family. Expressed at high levels in adrenal gland and brain and present at lower levels in lung, liver and colon, β-1,4-Gal-T6 uses magnesium or zinc to catalyze the UDP-dependent biosynthesis of glycosphingolipids. The gene encoding β-1,4-Gal-T6 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.

Specificity:

B4GALT6 polyclonal antibody detects endogenous levels of B4GALT6 protein.

Alternative names:

Beta-1,4-galactosyltransferase 6; Beta-1,4-GalTase 6; Beta4Gal-T6; b4Gal-T6; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6 ; Including the following 1 domains:Glucosylceramide beta-1,4-galactosyltransferase; Lactosylceramide synthase; LacCer synthase; UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase; B4GALT6

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human B4GALT6

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 45 kDa

Applications:

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com