Background:

β-1,3-Gal-T6 (beta-1,3-galactosyltransferase 6), also known as galactosyltransferase II or GAG GalTII, is a 329 amino acid protein belonging to the glycosyltransferase 31 family. β-1,3-Gal-T6 is involved in several glycan metabolism pathways. With manganese as a cofactor, β-1,3-Gal-T6 catalyzes the transfer of galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. β-1,3-Gal-T6 has a preference for galactose-beta-1,4-xylose found in the linker region of chondroitin sulfate, heparan sulfate and other glycosaminoglycans, but does not have activity towards substrates with terminal galactosamine or glucosamine residues. Ubiquitously expressed, β-1,3-Gal-T6 is a single-pass type II membrane protein localized to the Golgi stack membrane.

Specificity:

B3GALT6 polyclonal antibody detects endogenous levels of B3GALT6 protein.

Alternative names:

Beta-1,3-galactosyltransferase 6; Beta-1,3-GalTase 6; Beta3Gal-T6; Beta3GalT6; GAG GalTII; Galactosyltransferase II; Galactosylxylosylprotein 3-beta-galactosyltransferase; UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6; B3GALT6

Species reactivity:

Human,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human B3GALT6

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 37 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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